By: Joe Graedon November 4, 2024 22 Comments
    Antidepressants and Suicide: Why Don’t Peo…

    Antidepressants are, by definition, supposed to improve mood. They are prescribed to lift people out of psychological depression. In theory, drugs like fluoxetine (Prozac), paroxetine (Paxil) and sert…

    By: Joe Graedon October 31, 2024 69 Comments
    Long COVID Is Common and Scary!

    The immediate threat from a COVID infection is readily understood now. Most people who catch COVID-19 recover within a few weeks. However, doctors are still struggling with a different problem patient…

    By: Joe Graedon October 24, 2024 7 Comments
    Duloxetine Recall: FDA Flags Carcinogenic Risk f…

    Not Again! We have had it with carcinogenic contamination of pharmaceuticals. This has been happening far too often. The latest scandal involves more than 7,000 bottles of generic duloxetine (Cymbalta…

    By: Joe Graedon September 9, 2024 29 Comments
    Doctors Still Doubt Antidepressants Can Trigger …

    Most healthcare professionals have a hard time believing antidepressants can trigger suicide. It seems implausible that medications which are supposed to help relieve depression might make some people…

    By: Joe Graedon September 2, 2024 34 Comments
    Beware of Sudden and Unexpected Psychiatric Side…

    If you develop a rash within hours of starting a new medicine, you don't need Sherlock Holmes to help you make the connection. Some drug side effects are harder to identify. Psychological reactions ca…

    By: Dennis Miller, RPh August 21, 2024 4 Comments
    The Burden of Being 100% Accurate in Filling Pre…

    Dennis Miller, R.Ph. is a retired chain store pharmacist. His book, The Shocking Truth About Pharmacy: A Pharmacist Reveals All the Disturbing Secrets, can be downloaded in its entirety at Amazon for …

    By: Joe Graedon July 29, 2024 17 Comments
    How To Stop Venlafaxine: Very, VERY Slowly!

    It has taken the medical profession a very long time to acknowledge that many of the most popular drugs in the pharmacy can cause a kind of dependence. By that we mean such drugs can precipitate serio…

    By: Terry Graedon July 17, 2024 6 Comments
    Are There Toxins in Your Drinking Water?

    Does your drinking water contain contaminants you don't know about? Too many municipalities do dispense water with dangerous impurities. Even more alarming, the toxins you encounter in your water or a…

    By: Joe Graedon July 10, 2024 32 Comments
    Why Is Antidepressant Withdrawal So Hard?

    A few years ago it was estimated that one out of eight Americans took an antidepressant medication (JAMA Internal Medicine, Feb. 2017) daily. According to my current calculations, 46 million people no…

    By: Terry Graedon July 3, 2024 15 Comments
    Will You Gain Weight on an Antidepressant?

    Antidepressant medications are among the most widely prescribed drugs in the United States. People who take antidepressant medications for many years often complain that they gain weight. Several year…

    By: Joe Graedon June 27, 2024 5 Comments
    Oral Ketamine vs. Depression! What Took So Long?

    Drug discovery can sometimes seem interminably slow. A small study published in Biological Psychiatry (Feb. 15, 2000) was one of the first placebo-controlled trials to demonstrate that low-dose ketami…

    By: Joe Graedon June 24, 2024 1961 Comments
    Duloxetine (Cymbalta) Side Effects & Withdr…

    We have received so many complaints about duloxetine (Cymbalta) side effects that we have lost count. Far more disturbing are the number of people who tell us how hard it is to discontinue this drug. …

    By: Joe Graedon June 19, 2024 5 Comments
    Does Your Medicine Have a Boxed Warning? Why You…

    When people are poised to participate in risky activities, they are supposed to follow safety protocols. For example, sky divers exercise proper precautions and procedures before each jump. No commerc…

    By: Terry Graedon May 9, 2024 14 Comments
    Show 1315: Are We Medicating Normal Emotions? (A…

    This week on our nationally syndicated radio show, we examine the consequences of prescriptions for anxiety or grief. All of us, at some point in our lives, will experience some of these emotions. If …

    By: Terry Graedon April 25, 2024 2 Comments
    Show 1383: How to Calm Your Mind with Food

    Plenty of issues in the public eye could well make anyone anxious. Some people suffer more than others, however. What we feed our gut microbes–and ourselves–can make a big difference. In this epis…

    By: Joe Graedon April 22, 2024 28 Comments
    Can Lithium in Water Supply Prevent Dementia?

    The chances are good that you are exposed to some lithium almost every day of your life. That's because this natural element is plentiful in nature. It is found in rocks and soil all over the earth. T…

    By: Terry Graedon March 28, 2024 5 Comments
    Show 1350: Why Psychotherapy Matters: Lessons fr…

    If you tell your healthcare provider that you’re feeling anxious or depressed, chances are they will prescribe you a medication. Millions of people take anti-anxiety pills or antidepressants, and ma…

    By: Joe Graedon January 29, 2024 41 Comments
    Rediscovering Low-Dose Lithium for Mood Disorder…

    Lithium is a chemical element that is widespread in nature. You can find it in the earth's crust, in water and even in the food you eat. Depending upon where you live, there is a good chance that ther…

    By: Terry Graedon January 4, 2024 7 Comments
    Show 1368: Why Overcoming Loneliness Is Crucial …

    In this week’s interview, Dr. Robert Waldinger of Harvard University explains why overcoming loneliness is essential for our health. His research, summarized in The Good Life, shows that close relat…

    By: Joe Graedon January 4, 2024 22 Comments
    Authorized Generic Drugs Offer Quality and Affor…

    Have you ever heard of authorized generic drugs? Most people, including some physicians and pharmacists, have no idea what they are. That’s largely because the Food and Drug Administration tells the…

    By: Joe Graedon January 1, 2024 38 Comments
    Do Doctors Know How to Help Patients Stop Medica…

    Imagine for a moment that you are the CEO of a major drug company. What is the ideal product? Sadly, it’s all about money. In other words, what would be a highly profitable medication that doctors w…

    By: Terry Graedon December 14, 2023 3 Comments
    Show 1367: How to Evaluate Prescription Drugs

    In this week’s interview, Dr. Aaron Carroll of Indiana University discusses what we should take into account when we evaluate prescription drugs. How can we tell if the benefits would outweigh the r…

    By: Terry Graedon November 30, 2023 9 Comments
    Why You Should Eat the Mediterranean Way

    The Mediterranean diet has been associated with a number of health benefits. We have written previously about studies showing that a Mediterranean-style eating plan can protect the brain, reduce arthr…

    By: Joe Graedon November 12, 2023 47 Comments
    When a Drug Like Buproprion Smells Bad

    Some drugs have a distinctive odor. That’s a nice way of saying that some medications naturally smell nasty. For example, we have seen complaints that the blood pressure medicine diltiazem has a str…

    By: Joe Graedon October 26, 2023 6 Comments
    Do Conflicts of Interest Distort Antidepressant …

    How reliable are studies of medicines used to treat psychiatric conditions such as anxiety, panic or depression? A quick count of popular antidepressants reveals that more than 40 million Americans fi…

    By: Terry Graedon October 12, 2023 7 Comments
    What Should You Know about New Antidepressant Sp…

    The Food and Drug Administration approved a completely new type of antidepressant on March 4, 2019. The nasal spray called esketamine is supposed to help people who have not responded to standard anti…

    By: Terry Graedon September 24, 2023 7 Comments
    How to Fight Back Against SAD This Winter

    As the weather changes from a welcome chill in the air to wet and nasty to cold and icy, many people discover that they are spending more time inside. During short days, they get relatively little sun…

    By: Joe Graedon September 21, 2023 28 Comments
    Which Medicines Can Cause Severe Depression? Weg…

    Most people experience sadness or depression sometime during their lives. Divorce, the death of a loved one, work-related problems or financial setbacks can all trigger severe depression. Once the cri…

    By: Joe Graedon September 7, 2023 6 Comments
    Antidepressant Combination (Amitriptyline &…

    Mixing and matching medications can lead to pharmaceutical mess ups. This is especially true when the drugs do not go well together. We have been writing about dangerous drug interactions for about 50…

    By: Joe Graedon September 4, 2023 16 Comments
    Psilocybin from Mushrooms Can Ease Depression

    Psilocybin is the psychoactive compound in hallucinogenic mushrooms. Humans have used this "magic" mushroom compound in rituals for thousands of years. Psilocybin from mushrooms alters sensory percept…

    By: Terry Graedon July 13, 2023 4 Comments
    Exercise Is Effective Treatment for Psychologica…

    Exercise may help people overcome mild to moderate depression. Previous studies have shown that younger and middle aged people benefit. (Keep reading for more details on those.) Now we have evidence t…

    By: Joe Graedon July 10, 2023 350 Comments
    Can Chantix Cause Depression?

    The stop-smoking drug varenicline (Chantix) was first approved by the FDA on May 11, 2006. It wasn't long before millions of people were taking this oral medication to help them quit cigarettes. The i…

    By: Terry Graedon June 29, 2023 9 Comments
    Usual Antidepressants Don’t Help New Type …

    According to the CDC, 16 million adults will suffer from depression this year. This illness has a negative impact on mood, thinking and behavior. It takes the joy out of activities that are normally p…

    By: Joe Graedon June 22, 2023 15 Comments
    How Long Will Dizziness Last After Stopping Lexa…

    It is always smart to have an exit strategy. That is just as true when you begin taking a prescription medication as when you take a new job that might or might not be quite suitable. Doctors and phar…

    By: Joe Graedon May 28, 2023 3 Comments
    Prednisone Can Cause Anxiety, Depression and Ins…

    Corticosteroids are both a blessing and a curse. They can calm a serious allergic reaction and reduce inflammation. People with asthma may profit from a drug like prednisone during a flareup. Patients…

    By: Terry Graedon May 25, 2023 2 Comments
    Vitamin D Supplements for Babies May Boost Kids&…

    Vitamin D is an essential nutrient for both children and adults. Long ago, scientists dubbed it the "sunshine vitamin" because skin can synthesize it in the presence of sunlight. Doctors in northern c…

    By: Joe Graedon May 25, 2023 11 Comments
    Will Ketamine Really Battle Life-Long Depression…

    People with depression have a really tough time. Not only does the condition suck all of the joy out of life, the medications used to treat it have some potentially serious side effects. Moreover, ant…

    By: Joe Graedon May 21, 2023 7 Comments
    Are You “Addicted” to Your Prescription Medi…

    Before you read another word, rethink the term addiction! It is loaded with emotional baggage and is a terrible description of drug dependence. It often implies character flaws or vulnerability and fr…

    By: Joe Graedon April 17, 2023 0 Comments
    Are Old Antidepressants (MAO Inhibitors) Still H…

    It is estimated that depression affects as many as 1 out of 10 Americans. Teenagers and young adults are even more vulnerable, with as many as 17% impacted. There are ongoing questions about the effec…

    By: Terry Graedon March 15, 2023 8 Comments
    Can You Overcome Depression with Exercise?

    Millions of people globally are suffering from depression or anxiety. There is some good news, however. An overview of systematic reviews (an "umbrella review") of more than a thousand randomized cont…