wellbutrin and budeprion pills

Some drugs have a distinctive odor. That’s a nice way of saying that some medications naturally smell nasty. For example, we have seen complaints that the blood pressure medicine diltiazem has a strong plastic-like odor. There have also been reports that some formulations of the diabetes drug metformin smell like stinky old socks or “dead fish” (Annals of Internal Medicine, Feb. 16, 2010). Such smells may be “natural,” but when the antidepressant bupropion smells bad, beware. It could be bad news!

A Reader Says his Bupropion Smells Bad:

Q. I take bupropion 300 mg XL for depression. I’ve not had any problems with it previously, but the latest bottle smells like rotten eggs.

I called the pharmacist and they told me that some drugs smell and not to worry about it. They said that the drug is safe to take. True?

A. The drug company that developed the antidepressant bupropion (Wellbutrin) over 30 years ago was Burroughs Wellcome. A scientist who worked there told us that the terrible smell you describe indicates that the drug is deteriorating. He maintains that this odor is a sign of potential manufacturing problems.

The first generic formulation of Wellutrin XL 300 was given the name Budeprion XL 300. This long-acting bupropion came out towards the end of 2006. By February of 2007 we were hearing from readers of our syndicated newspaper column that they were having problems with this extended-release formulation.

An Experts Weighs In On Bad Smelling Bupropion!

One of the great blessings of writing a syndicated newspaper column is that we hear from people all over the world. Often we get comments from “regular” readers. But sometimes we get a message from an expert.

That was the case with the report above that “bupropion smells bad.” In our answer we mentioned one scientist (Steve) who worked at Burroughs Wellcome.

Just recently we hard from another scientist (probably Steve’s boss). Here is his message:

Q. You had a question from a reader recently about bad-smelling bupropion. I was Director of Chemical Development at Burroughs Wellcome when the extended-release formulation was being developed. The API [active pharmaceutical ingredient] (HCl salt) is reasonably stable, but the free base is not.

Various generic companies have tried to reverse engineer the extended-release formulation with mixed results. I am not surprised to hear continued reporting of generics literally stinking because of decomposition.

A. We have heard from another key Burroughs Wellcome scientist involved in the development of the antidepressant Wellbutrin (bupropion). He also told us that any unpleasant odor associated with this medication indicates chemical breakdown likely due to faulty manufacturing processes.

One patient described the odor as “like horrendous rotten eggs.” Another stated that the new bupropion prescription “smells like sewer gas” and noted that it caused stomach issues. A different reader also complained that a bupropion refill smelled “like a sewer pipe.” He added, “I used to be a plumber, so I know the smell.”

We were among the first to alert the Food and Drug Administration to problems with generic bupropion in 2007. At first, the agency denied that there was a problem. It attributed patient complaints of adverse reactions and diminished effectiveness to psychosomatic responses.

After five years, however, the FDA finally admitted there was a problem with some generic bupropion formulations. They were recalled. We fear the FDA has let down its guard in recent years.

You can read the whole story at this link.

The Generic Bupropion XL 300 Scandal:

Some people complained of insomnia, headaches, dizziness, anxiety, irritability, nausea, tremor, mood swings and panic attacks. Others reported that their depression had returned with a vengeance.

Many of the people who took this first generic version of Wellbutrin XL 300 complained to us that:

“the bupropion smells bad.”

We asked readers to send us their Budeprion XL 300 bottles so we could forward them to the FDA for analysis. The smell was distinctive.

Actually, that’s not true. The odor was awful. We specifically asked the FDA to investigate why the bupropion smells bad. The agency never responded.

The FDA Flip-Flops on Generic Bupropion:

We continued to badger the FDA for five years because we felt that lives were at stake. If an antidepressant does not work as expected, it could lead to severe depression and thoughts of suicide. Despite our continuous complaining, executives at the FDA kept insisting that the generic bupropion was fine and dandy.

The agency eventually concluded that there were indeed problems with Budeprion XL 300 and a few other generic versions of bupropion. On October 3, 2012, Teva’s generic formulation of Wellbutrin XL 300 was removed from the market because it was:

“…not therapeutically equivalent to the reference listed drug (RLD), Wellbutrin XL 300 mg.”

You can read about the whole sordid scandal at this link.

Other Readers Complain That Their Bupropion Smells Bad:

Don asks:

“Anyone know why my generic Wellbutrin (bupropion) smells like vinegar?”

Robert says his slow-release form of bupropion smells bad:

“I have been taking bupropion SR for years. My doctor changed the dosage. With that, my pharmacy changed the manufacturer. I have never noticed an odor with previous dosages. This formulation has a strong sickening sweet smell. This smell cannot be right. I am returning it to my pharmacy.”

J.R. also says his bupropion smells bad and he is a retired chemist:

“I just got a refill of bupropion XL generic from India. The pills smell horrible. After taking this drug for many years, I think I would have noticed if any of the suppliers I used in the past made tablets that smell objectionable. I would say the odor is sulfide-like.

“The pharmacy said the smell was from the desiccant insert in the original package being exhausted. I have not taken any yet, and I really do not want to. If I wanted cheap drugs from India, I know places I can order them for less than my co-pay at the pharmacy. I don’t think I am a nut job. I was an organic chemist and botanist by trade (now retired).

“The patent does not protect the end product in India. It only protects the way it is manufactured. That pretty well ensures that they will make a drug with a different set of reagent chemicals then what a licensed company in the western hemisphere would use. Will it end up the same? All I can say is: maybe – MAYBE NOT.”

Lest you think this is old news, we recently heard from Charlotte. She reports:

“The bupropion pills I just received smell so bad! I can’t find out why. Do you have any idea? They were manufactured abroad!”

A. Many years ago we uncovered problems with certain generic formulations of the antidepressant Wellbutrin (bupropion). A medicinal chemist explained to us that a bad smell indicated serious manufacturing flaws. This challenge apparently still exists for some generic drug companies.

Brand name Wellbutrin is expensive in the US! If Wellbutrin is purchased from a reputable online Canadian pharmacy the same brand name medication would cost under $200 for a three month’s supply.

You can learn more about buying brand name drugs from Canada in our eGuide, Saving Money on Medicines. This online resource is available under the Heatlh eGuides tab.

Final Words:

Buying the brand name Wellbutrin XL 300 is not a viable option for most people. That’s because the retail price for 30 pills is around $2,000 according to GoodRx. Even with a coupon the brand can cost more than $1,8000.

That means a year’s supply could amount to something in excess of $21,000. Very few insurance companies are willing to pay that much for the brand name medicine. They don’t seem to care if the generic bupropion is up to snuff, just as long as it doesn’t cost too much. That’s why consumers may have to find other ways to get high quality medicines at an affordable price.

Do you know someone who is taking generic medication? Who isn’t these days? We only wish the FDA did routine testing of generic drug quality. Here is a message we received from the Office of Generic Drugs (OGD) at the Food and Drug Administration on October 30, 2023.

The FDA’s Office of Generic Drugs:

“…discontinued product sample testing requests.

“This email is in response to your concerns with bupropion extended-release tablets.  Thank you for advising the FDA of your concerns with the “bad smell” of the product. We take safety complaints about generic drug products very seriously. Your information was forwarded to the Office of Generic Drugs’ Division of Clinical Safety and Surveillance (DCSS) for evaluation. DCSS works with our colleagues in CDER [Center for Drug Evaluation and Research} to investigate potential product quality problems.

“If you have not already done so, please submit a MedWatch report, so that the Division of Clinical Safety and Surveillance (DCSS) can analyze it, track it, and compare it to similar reports should they exist.  The more information you can provide on the MedWatch form related to the problem, the more helpful the report will be to the FDA.  For example, please tell us the name of the manufacturer, lot number, etc.  The MedWatch Voluntary Reporting Form can be easily filled out online at the following FDA website:

https://www.accessdata.fda.gov/scripts/medwatch/index.cfm?action=reporting.home.

“You may also report via the telephone at 1-888-463-6332.”

I wish I could trust the FDA to actually do something about bad-smelling bupropion.

What do you think?

Please share your experience with generic drugs in the comment section below. Our eGuide to Saving Money on Medicine can be found under the Health eGuides tab. It shares some insider information about getting brand name drugs from Canada.

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  1. Melissa
    Reply

    I just opened my Bupropion HCL SR 150 mg for the first time in a few weeks. The first time I took it I got an awful migraine, and it smells of rotten eggs. I think I’m going to ask my doctor to switch me to something else, as the FDA doesn’t seem to care that something is definitely wrong with these pills.

  2. Susan
    Reply

    Oh, they have definitely let it slide. I take Buproprion, and my first batches were fine. In my second year my pharmacy got a new supplier. Smelled like rotten eggs–every batch. My psychiatrist told me to protest but the pharmacy kept saying it was normal. When the doctor tells me no, I’m listening to my doctor, not the people paid to get the pills in my hand.

  3. Angel
    Reply

    Opened bottle 150xl with gs1 on it. Just few days over a month from fill date. Suddenly strong sulfur smell, but just the day before… nope. So it sounds like deterioration to me. Horrible. Something needs to be done. I live in a small town, and pharmacy may have same batch, so if I refill, it may still be bad.

  4. .Jules
    Reply

    SOLCO MFR BUPROPION SR 200MG TABLET. QUALITY AND EFFICACY CONCERNS:
    Issues with strong sulfur odor started this spring and has worsened since. Contacted manufacturer, to no avail. Sought different supplier only to receive max quantity of pungent malodorous tablets. Reached out to Solco again, and PharmD of supplier. I was advised “sulfa like smell normal” by PharmD. Now, I may be a layman, yet I know that sulfonamides and sulfur are not interchangeable, and communicated as such, and the intolerability was not imagined. The PharmD sent out another 360 tabs, which were also malodorous, albeit slightly less pungent. Efficacy is noticeable.
    Interestingly enough, Solco rep contacted me this round, only to close claim within a week (tablets were to be sent in for further testing!?) Closure report concluded that despite change of acid stabilizers, product is still acceptable as per FDA guidelines.
    I am here to report differently!? WHAT ABOUT EFFICACY, AND LACK THEREOF?

    • Terry Graedon
      Reply

      We have heard from the scientists who first worked on bupropion that a bad smell of this drug indicates that the compound is deteriorating.

  5. Gladi
    Reply

    I stopped taking Bupropion because of the rotten egg smell. I couldn’t believe this was normal when I asked about it because the first bottle was fine but after that one the smell was noticeable, and the only effect of this pill was an upset stomach.

  6. Tracy
    Reply

    I had the same problem with the Accord pills. I did some research and found that Accord is owned by Intas Pharmaceuticals, and the FDA sent them a warning as recently as July 2023 that their manufacturing practices are subpar, and they need to bring them up. They had been cited before but have failed. Interesting read below:

    https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/intas-pharmaceuticals-limited-652067-07282023

  7. Pete
    Reply

    I have the sulfur/egg smell every time I open my generic Bupropion 300 XL. Mine are made from Accord and the pills are white circles with a GS2 printed in them.

    I didn’t have this issue when I got my first 90 day supply from a manufacturer where the pills came in their own factory sealed container, but these GS2 pills I received after switching pharmacies reek of eggs 1-2 months after their fill date.

  8. Cheryl
    Reply

    I have taken BUPROPION HCL SR 150 MG TABLET SUSTAINED-RELEASE 12 HR for over 15 years. the past year I have stopped taking them due to the smell, the purple ones reek like rotten eggs Solco Healthcare is the manufacturer. I know I can request a specific manufacturer, the white ones from Teva don’t smell but its not worth the stress. I will have to find another medication.

  9. J
    Reply

    I had this experience with the 200 mg pills as well. Filled at CVS but sourced from an Indian pharmacy.

  10. Roy
    Reply

    I was Director of Chemical Development at Burroughs Wellcome when the extended release formulation was being developed. The API (HCl salt) is reasonably stable, but the free base is not. Various generic companies have tried to reverse engineer the extended-release formulation with mixed results. I am not surprised to hear continued reporting of generics literally stinking because of decomposition.

  11. Isabelle
    Reply

    You don’t get something for nothing. Generics are just inferior. That’s why they’re cheaper. The manufacturing plants are always in trouble for being unsanitary and unmonitored.

    My Alprazolam was not working anymore and I found that it was coming from plants in India with multiple infractions of the law and “FDA standards” (if they have any).

    Managed to find a pharmacy that used a supplier in America (associated with Phizer). Made a big difference. Unfortunately, they can’t always get their meds from that supplier. Back where we started.
    I just can’t stand it!

  12. Rosa
    Reply

    I started smelling rotten eggs in the morning and since I have a gas furnace, I was concerned. The gas company sent a tech and he found nothing wrong. But, I kept smelling the rotten eggs. Then, one morning, as I was taking the Wellbutrin generic which I had been taking for years, that I realized it was the pills!! Ugh. Now what?

  13. Lee F
    Reply

    This doesn’t surprise me. Generic bupropion is made in India and has had issues with sub-standard fillers for years. I couldn’t stay on the generic for more that 2 weeks before I asked for a brand name-only script. Brand name IS different. The gas and diarrhea disappeared instantly. The depression actually was affected. The generic is crap. I had a Good Rx coupon for the brand name for a year, and then the coupon expired and couldn’t be extended, so the price went up to $500/month. I am now ordering Wellbutrin from an online Canadian pharmacy. U.S. Customs in Los Angeles has confiscated it twice in 10 years, which is a risk I continue to take to get the medication I need. But for $150 I get 3 months. Whenever I travel outside the country, I go into pharmacies to see if brand-name Wellbutrin is available. (I bought it in St. Maarten recently. It’s not available in most Mexican pharmacies.) I’ve contacted the FDA and my congresspeople to no avail. I don’t know what else to do.

  14. Carey
    Reply

    In my experience, all prescription medications smell, either rancid or at least like chemicals. I leave the tops off all of them, plus many OTC. I know that’s not what you are supposed to do, but I couldn’t take them otherwise.

  15. Fred
    Reply

    It is a shame that we lack confidence in the government agencies tasked with protecting us. I say we need to offer better compensation and rewards for good service, better inducements and protections for whistle blowers, and stronger penalties for malfeasance.
    Think ‘Singapore’: their public servants are well-respected and well-compensated, and they strive to earn these rewards. Those rare few who abuse their positions are usually found out and punishments are Draconian: aside from fines and possible imprisonment, they are effectively unemployable thereafter: their lives are pretty much ruined. This carrot& stick approach tends to keep government employees honest and incorruptible, which in turn earns them respect and honor.

  16. Beverly
    Reply

    I sent my bottle of Budeprion 300XL to you in 2006 because the pills didn’t work and caused terrible side effects. I tried all strengths and versions of the generics with the same results. Luckily, my new insurance covered the name brand which cost $125 for a 3 month supply. Then on January 1, 2023, my Medicare United Advantage plan with Caremark stopped covering it. I tried the generic but it made me really sick.

    Because I had tried so many different antidepressants with bad side effects, I qualified for 35 TMS Transcranial Magnetic Stimulation treatments which alleviated my depression. No one knows how long it will last, and my insurance won’t approve additional treatments. Who is able to pay $2000 a month for name brand Wellbutrin 300 XL?

  17. Cherrie
    Reply

    I began taking Wellbutrin SR in 2000. My insurance changed my Rx to generic not
    long after. I took Sandoz generic brand until my pharmacy permanently closed in 2018. Since then all that is available in my area (medium size metro) is generic Solco Bupropion SR or brand Wellbutrin name SR.

    Solco smells like horrendous rotten eggs. It makes me gag. Solco gives me more energy but also causes a ton of anxiety. Wellbutrin brand makes me apathetic & don’t work well for depression. Solco doesn’t have a steady effect throughout the day like Brand, instead dumping all at once twice during the 12 hrs. For that reason I can’t tolerate my full dose. I am concerned about the smell.

    I took all of the pills out of the bottle once and let them “air” out. The smell went away. But after being back in the bottle (mfr bottle) the smell came right back. This has happened in opaque mfr and orange transparent pharmacy bottles. The Solco doesn’t smell in my daily pill containers – just a few in the slot.

  18. Jay
    Reply

    I avoid the odor of rotten eggs of Bupropion by simply keeping the pills refrigerated.

  19. Toki
    Reply

    I’ve been taking Bupropion XL 150Mg for years, and recently my pharmacy switched to pills marked with GS1. A search says these are made by Accord Healthcare Inc. My bottle, filled 6/15/23, smells stronger than just sulfur and smells like sewer gas. I’ve never had it smell like this, and I’ve been having stomach issues since I started taking the new bottle. I’m attempting to get my Dr to re-send the script to a different pharmacy.

  20. Maria
    Reply

    The pills in my generic buprobion last bottle in 2023 stink like strong glue. It is not the plastic container. I try with a different container, and the same smell that’s in the pills. I feel like I am taking glue.

  21. Tony
    Reply

    My newest Bupropion refill comes from Slate Run Pharmaceuticals and the smell of them is like a sewer pipe.
    I used to be a plumber so I know the smell.

    I just decided to look for this problem and found out others are getting these literal pos’s only from Slate Run Pharma.

    I read where others have smelly urine and body odor too.
    I have the same problem since these came. I stopped taking them and the urine is back to normal.

    I’m going to take them to my PA to let her GAG .

    I’ve been taking Bupropion for over 5 years and NEVER gaged from openning a bottle of them.

    Is Slate Run playing a joke on us? I know parts of India are rancid. Are they using their rancid water to produce these pills?! 1/11/23

  22. Arleen
    Reply

    2 weeks ago, my pharmacy switched my manufacturer of Bupropion SR 100 mg to Dr. Reddy’s. I thought that my surfacing depression, crying. nervousness, and insomnia was in my head. This was OVER THANKSGIVING, when I was visiting my son, daughter in law and granddaughter. The visit was ruined because the drug WAS NOT WORKING and the smell indicated deterioration. I was a wreck. The doctor switched the mfg.. two days ago and now I am slowly becoming my self again.

  23. Leah
    Reply

    I have noticed that my last 2 bottles of Buproprion Xl 24hr 150 mg have smelled like sulfur. The smell is so strong when I open the bottle that I have to hold it as far away as possible to keep from gagging. They are 90-day supply and I’m 2/3 through the 2nd bottle, so I’ve been taking them for 150 days now.

    The past few of months I’ve noticed an embarrassing odor coming from my private area. I first thought it was an incontinence issue so I started wearing pads daily, but that did not help. I then started doing an internal cleanse regularly, and that didn’t help either. I then realized the smell was not on my clothing as you would think if it were incontinence. I then figured out the smell is just resonating from that part of my body, more prominent when sitting in an open leg position. When I would describe the smell to my husband or doctor, I struggled at first, but then eventually it came to me…sulfur!

    And then I started to connect the dots. I haven’t been to my doctor since, but I feel certain that the strong odor of the Bupropion has been resonating from my body.

    Has anyone else noticed this? I’m sorry if this is TMI!

  24. Gina
    Reply

    I got my generic Wellbutrin SR 200mg refilled from Optum Rx, which is my insurance’s online pharmacy. It is made by Slate Run. I have a 90-day supply, and both bottles smell disgusting, kind of like rotten eggs mixed with chemicals. My normal reaction would be to throw anything that smelled like this away and definitely not swallow it! But this medication is important so I have to stay on it.

    I have an ileostomy and the smell is very similar when I empty my bag. This, is after being completely digested by my small intestines. There has to be something in the Wellbutrin that is making that smell. We deserve to know what it is so we can decide whether we want that in our bodies or not!

  25. Michael
    Reply

    I’ve got two bottles of Bupropion ER 150mg that have a rotten egg smell. They never smelled like this in the past. I called my pharmacy and asked them what to do. They told me to contact the manufacturer and that my pharmacy isn’t replacing them. Anyone know if this is the real procedure for something like this?

  26. Celeste
    Reply

    I take the twice-a-day 150 SR. I used to get Sandoz brand. which was great. Now I am sent Slate which smells strongly of garlic. My most recent bottle of 90 day supply smells absolutely rancid. I have not felt well since trying to take these pills. Not sure what can be done other than changing meds. I did contact the pharmacy and am waiting for a response.

  27. Autumn
    Reply

    I was taking the XL 150 2x a day, and I never noticed a smell at all. I recently was changed to a 300 SR and 150 SR, and the both stink so bad it’s almost nauseating. I just googled it because I had not taken this type or dosage before, and now I’m concerned. I’ve waked up with some bad headaches and some other things that are new. How do I find out if this is the cause? My insurance won’t just pay for replacements.

  28. Dawn
    Reply

    My new bottle of bupropion xl 300 smells like rotten eggs!! My pharmacist says it’s normal, and that’s the only kind they can get anyway. I’ve been on the drug for years and never ever smelled this before! But I just have to keep taking it :(

  29. TJ
    Reply

    I have been taking Bupropion XL for a few years w/o any issues. My latest refill was 6/20/22 for a 90-day supply. For the first time, when opening the bottle today, 8/11/22, the smell was horrendous. I’ve had the bottle for almost 2 months w/o any odor. Why suddenly is the medication smelling like sulfur/sewer?? It is AWFUL!!!!!!!! And I still have over a month before my next refill.

  30. Stephen
    Reply

    My most recent bottle of Bupropion XL smells like rotten eggs. This is the first time that this has happened to me. I called my pharmacist, and they told me that their supplier only has this new manufacturer available. And that their whole bottle smells like rotten eggs. I was told there was nothing they could do about it.

    What can I do? Is there an agency or group where I can file a complaint about this drug?

    I have already had a terrible time with the product that was recalled. I was actually going to a psychologist trying to find out why I was having terrible anxiety. Turned out the medicine I was on was just not working because it was bad.

  31. Pamela
    Reply

    I take Bupropion HCL 200mg by MFR Reddy’s, and it has a pungent sulfur/vinegar smell. I didn’t take it for over a year, got a refill and the smell is exactly the same. The physical reaction is just shy of the gagging I experience when I smell old Vitamin B pills. I think it’s working but I’m not sure. It’s not a significant improvement. I have raised the issue with the smell in the past and been advised that it is normal…

  32. Kerri
    Reply

    I am currently having issues with a particular generic form of bupropion SR. It smelled of sulfur and caused high blood pressure, woozy feeling, and a definitive return of my depression. My pharmacy tried to order a different brand, and apparently they have a contract now to only order the bad stuff. About to go through the problem of switching pharmacies.

  33. A D
    Reply

    I had a bupropion XL prescription filled about two weeks ago, and this morning opened the bottle for the first time to find that the pills smelled strongly of sulfur. I have taken this medication for roughly ten years and have taken this particular generic (which is manufactured in India) for more than a year, and this has never happened before. I returned to the pharmacy, but the pills they had smelled just as bad. I tried a different pharmacy location but their generic (from the same manufacturer) also smelled like rotten eggs.

    Unfortunately, they carried no other manufacturer’s generics, so my options are limited. I don’t know what happened to this batch, but clearly something is different. Being allergic to sulfa antibiotics, I am especially reluctant to take something that smells like sulfur.

  34. Ellen
    Reply

    FYI, Valisure does not test any medication covered by Medicare or Medicare-affiliated Rx plans such as the United Health Care (UHC) plan sponsored by AARP. I know this because I contacted them about my Bupropion Rx that I get through OptumRx, which is affiliated with my Medicare Rx supplemental plan.

    I’m guessing a lot of subscribers to this newsletter will be disappointed to hear this news, as was I.

  35. Robert
    Reply

    However, Valisure is unavailable for medicare or medicaid patients. So, unfortunately, those with that type of insurance do not deserve clean drugs???

    • Terry Graedon
      Reply

      Everyone deserves drugs that are safe and effective, regardless of the insurance used to provide them.

  36. Robert
    Reply

    I have taken wellbutrin xl 300 mg back in 2006, when they put the generic out and it was never effective. I also, have found a few times were either atenolol or metroprolol ER 50 mg or 100 mg smell was off, and left a bad taste in my mouth, not only did it smell bad, but it also seemed to have more bad side effects, like overall malaise or disruption of sleep.

  37. Karen
    Reply

    I switched back to Wellbutrin after the different generic formulations were not effective. Fortunately, I have a coupon that results in a moderate co-pay. I did not notice the smell of the generic pills. However, after switching back to Wellbutrin I no longer had what was an odd body odor. Also, I only need 150mg of Wellbutrin for effective results as opposed to the 300 mg of the generic which was inconsistent in efficacy.
    I don’t believe the generics are sufficiently equivalent.

  38. Jody W
    Reply

    Thank you for a great article! We need to keep our drugs pure, even if that means China and India lose business. We have to trust our medications. Right now, I dont.

  39. Paul
    Reply

    The N-Acetyl L-Cysteine smells awful, and the Quercetin & Bromelain makes me feel bad.

  40. David
    Reply

    I take bupropion 450 XL. I haven’t noticed a smell with them. Have there been reports of suspect batches of the higher dose?

  41. Margaret
    Reply

    I have had a bad experience with the generic version of Welbutrin XL 300. I was on the name brand Welbutrin XL 300 until our insurance carrier changed. The local pharmacy immediately began dispensing a generic buproprion. Not only did it NOT work, it caused me additional problems like anxiety attacks. We were told that we had to apply for a ‘variance’ from our health insurance provider in order to have the brand name Welbutrin XL300 changed from the “non-formulary” list of drugs. This required time and effort, involving letters (not one– but several) from my doctor to the insurance company. This happened about 12 years ago. Since then, I have always made a note in my medical records that I cannot take the generic version of Welbutrin XL300.

    We now buy Welbutrin from Canada which costs us about $173 for a 3 month supply. That is a straight price, no insurance required, only a hard copy prescription from my doctor which we fax to the Canadian pharmacy. We are now on Medicare so cost is important–but so is getting the drug that works as it should.

    As a side note, we also order my Synthroid from the same Canadian pharmacy at a MUCH better price than anywhere in the US. Why is that ????

  42. C
    Reply

    I was reading a post on a county chatlist from an older man taking about his difficulty getting around and the fact he is on 15 drugs.
    I thought to myself, that’s his problem, not age but the 15 drugs.
    Now the pharmacies are pushing bad drugs with the exception of one.
    Only one seems to care about their client.
    How low the health system has fallen..
    But hey if FDA approved, it must be safe…….NOT

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