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It is that time of year: sniffling, sneezing and snorting because of allergies. Such symptoms didn’t used to be a big deal. During a time of COVID-19, though, people look at you with anxiety and trepidation if you sneeze or cough within 20 feet of them. What can you do to ease those symptoms and stop the stares? You’ve probably never heard of NasalCrom nasal spray for allergies. It doesn’t get the kind of attention that many other allergy treatments receive. But it is surprisingly effective.
The BIG Money is on Antihistamines and Steroids:
Chances are good that you have seen television commercials for a wide variety of symptomatic treatments. There are oral antihistamines such as loratadine (Claritin), cetirizine (Zyrtec) and levocetirizine (Xyzal).
The Claritin commercials promote spring as the “Most Wonderful Time of the Year.” As the family comes rushing downstairs to embrace the great outdoors, the announcer says:
“Claritin provides non-drowsy symptom relief from over 200 indoor and outdoor allergens day after day.”
The Xyzal owl tells allergy sufferers that “bedtime means it’s time to take Xyzal.”
He concludes:
“be wise all, take Xyzal.”
The commercials make it seem as if such products are the ideal solution to solving allergy symptoms. There is one drawback to using some antihistamines for the entire allergy season. Stopping them suddenly after months of use can lead to unbearable itching that may last six weeks or longer. Read more about this unexpected reaction at this link.
Corticosteroids Seem Ideal:
Then there are corticosteroid nasal sprays. Products such as fluticasone (Flonase) and triamcinolone (Nasacort) have been joined on over-the-counter shelves by mometasone (Nasonex).
In the Flonase commercial, an enormous green monster rises out of the earth, while the narrator tells us:
“allergies don’t have to be scary.”
Apparently one person on earth got that message. He watches with interest while the others scream and flee. That’s because he sprayed Flonase in his nose before leaving home.
Such steroid nasal sprays are effective against allergy symptoms. However, they can cause side effects of their own, including changes in the sense of smell or taste. Long-term use may increase the risk for cataracts.
What About NasalCrom? Cromoloyn for Allergies:
One kind of allergy medicine that you probably won’t see advertised on television is cromolyn (NasalCrom). This drug works differently from steroids as well as antihistamines.
Rather than counteracting histamine after its release or calming chemicals in the nose with cortisone-like compounds, cromolyn stabilizes mast cells. That keeps them from reacting to allergens and discharging inflammatory agents.
The origins of this medication are in a natural remedy called bishop’s weed (Ammi visnaga). The prescription drug NasalCrom was introduced in 1983. It went over the counter in 1997. Not all pharmacies stock NasalCrom, but it is available online.
The drug is considered quite safe, although some people experience temporary sneezing or irritation. The biggest downside is that the instructions say it should be used three or four times a day, which can be inconvenient.
One reader reports:
“I’ve been using NasalCrom very successfully for a few years now, ever since my pharmacist recommended it. It clears up my spring and fall allergies with one spritz a day in the a.m. The trick is to start it before the season begins.”
Another agrees:
“I had suffered severe seasonal allergies for years. Then a few years ago I tried NasalCrom. At first, I had to use it three or four times a day, but it worked quickly and now during allergy season I need it only once in the morning and again at bedtime.”
NasalCrom Is Different!
To quote the famous Apple computer ad from decades ago: “Think Different.”
Q. I read in a health newsletter a few years ago that OTC NasalCrom would help allergies. My husband suffered with runny nose and nasal congestion for years.
After using NasalCrom, his allergy totally disappeared. I didn’t have to iron many handkerchiefs after that, so I was delighted!
Another reader wondered what her husband could do for his allergies. His throat clearing was driving her crazy:
Q. My 66-year-old husband clears his throat too much. He says he has drainage that has to be cleared in order to breath. He has tried many products and techniques with no relief.
The allergist tested and found the usual culprits: dust mites, ragweed and dogs. I keep the house as free of allergens as possible.
The prescription allergy nose spray didn’t help. Now an ENT doc wants to do an invasive test for GERD. That doesn’t make sense to me. We’d appreciate a solution.
A. We heard recently from a man whose wife had somewhat similar symptoms:
“She has long bouts of coughing due to congestive heart failure and allergies that cause a lot of sinus drainage. The trouble is she reacts badly to most antihistamines. What can we try?”
We mentioned NasalCrom (cromolyn). This OTC nose spray is used preventively and reduces the inflammatory response to allergens.
Later, we heard back from him:
“NasalCrom had a prompt effect. The postnasal drainage is significantly reduced. Her cough gradually improved and then dramatically disappeared. Her cardiac rehab is going well, with attention to exercise, diet and sleep.”
Mast Cells Cause a LOT of Mischief:
Mast cells are found in your eyes, nose and lungs (and other places in your body) that are highly sensitive to allergens.
Think of mast cells as floating mines. When they come into contact with allergens like ragweed pollen or dust mite poop, a switch gets thrown on these cellular “mines” and all hell breaks loose.
Mast cells start releasing histamine and other chemicals called kinins (pronounced KYE-nins), which then turn on a cascade of other nasty things like leukotrienes and prostaglandins. The end result is sneezing, itching, inflammation, and congestion.
Stabilizing Mast Cells:
If you can stabilize mast cells and make them less sensitive to allergens they appear to be less likely to trigger the release of all those nasty chemicals described above. That way you can prevent symptoms at the source of the problem.
We think such an approach may be more logical than trying to block the effect of histamine with antihistamines. And we think it is safer than squirting steroids in your nose on a regular basis. Some of the corticosteroid is absorbed into your body.
Shutting the Barn Door BEFORE the Horses get Out:
Think of it this way. If your mast cells are like a barn holding in a bunch of wild horses (histamine molecules), then what would be more efficient–reinforcing the door and walls of the barn to keep those wild histamines inside or trying to protect all the grass in your pasture from having those histamine “horses” nibbling away at it?
Antihistamines are like a chemical barrier that tries to protect your grass once the horses are out of the barn. But they are not 100 percent efficient, and some histamine will always find a target and wreak havoc. Keeping the barn closed tightly (or the mast cells stabilized) seems to us to be a more effective approach.
Nasalcrom to the Rescue:
The compound cromolyn stabilizes highly sensitive mast cells in the lining of the nose and lungs so they can better resist the onslaught of pollen. It won’t cause drowsiness or cognitive impairment and, if used regularly, it is quite effective. It can be taken for up to twelve weeks. Unlike decongestant nose sprays, there is no need to fear developing dependency.
Side Effects of NasalCrom:
Cromolyn is very safe and does not cause drowsiness or rebound nasal congestion the way OTC nasal decongestants can. Some people may experience temporary sneezing, nasal burning, or a bad taste in their mouth. You can read more about the long-term use of cromolyn at this link.
Downside:
The official instructions suggest using NasalCrom three or four times a day to really benefit. Some experts believe it is less effective than intranasal corticosteroids. We suggest that it is safer and worth a try if you are the kind of person who can spritz your nostrils three to four times daily. As mentioned above, some people get by with one or two sprays.
Share your own experience with cromolyn below in the comment section. You may want to listen to our podcast about allergies with Dr. David Peden and Dr. Tieraona Low Dog. They offer practical information and nondrug options for controlling symptoms. Here is a link to managing the misery of allergies.
Jill
I ran across this post after searching in the U.S. for cromolyn sodium eye drops, which I usually buy on my UK trips. They are the only things which keep my eyes from itching constantly due to allergies. I’ve tried every other allergy eye drop available here, and none help. I’m going to pick up some Nasalcrom to see if it can serve double duty – replace my current spray, as well as the eye drops. Maybe I can even stop with the daily oral antihistamine as well.
Lois
As I hear that it may take a week or so to work, can I take another antihistamine as well?
Ramona
I have been battling Sarcoidosis and Asthma for years with severe coughing spells, sneezing and congestion. I was getting sick like clockwork every year, fighting the same symptoms and going through the same miserable process of being prescribed my usual medication. Until I found a Pulmonlogist who prescribed Nasal Crom and one other prescription Nasal Spray. You guys, I felt better within a few days and was relieved that someone finally found the right treatment for my medical problems. Now I still have my bad days, but the Good Days Definitely Out Weigh them. THANK GOD and The Makers of Nasal Crom.
Lynne
I have been using Nasalcrom since about 1983, when it first came out. Antihistamines common then (Chlortrimaton, Benadryl) didn’t work for me — they didn’t even make me sleepy. Steroids were the only thing that helped my severe seasonal allergies. I even tried allergy desensitization shots — no luck. But while at the allergists office for my final visit, I saw an article about this new drug — Nasalcrom. I got a prescription for it, and my life changed! I only use it when I know I’m going to be exposed, before gardening or hiking in the summer, for example. I don’t have to build it up in my system because my histamine level is so much lower now (thank you NAET for that! — look it up).
I often recommend Nasalcrom to my clients (I’m a holistic practitioner) who have allergies, along with Hesperidin, a capsule made from citrus that also stabilizes mast cells. They have quite effectively changed my life.
RONALD
DOES IT HAVE ANY EFFECT ON BLOOD PRESSURE?
Pat
I’ve used NasalCrom for several years with much success. I only need it 2x a day now. When I reach the bottom third of the bottle I start looking for it in the store before I run out.
Alice
No matter how well I clean and dust with tea tree oil, I still have bad indoor allergies through the winter. And then comes tree pollen season. On your recommendation, I started using Nasalcrom this winter instead of a steroid spray which scares me. Had a pretty good winter, and now Nasalcrom is doing well with spring allergies. I also get such itchy red eyes that I cannot bear it. Recently tried an inexpensive eye drop, Alaway, which I will use for a few weeks. Helping a lot and allowing me to enjoy the outdoors in the spring.
Bruce
If you are already on Claritin, can the NasalCrom be used at the same time without issues?
Richard
I have been using NasalCrom for my allergies ever since my Doctor told me never to use any medication containing antihistamines. I usually get NasalCrom online.
Jackie
I’ve used Nasal Crom for years with very good results. Can’t find it in the stores anymore so I buy online.
KJ
I tried nasalcrom for my allergies about 1year ago. I had to stop using it as it caused dizziness / vertigo which didn’t clear up until I stopped taking it.
It’s one of the listed side effects and was quite unpleasant.
KD
Hi! I know it’s been a while since you commented but if you see this can you tell me how long after stopping Nasalcrom the dizziness stopped for you?
Peter
I used cortisone nasal sprays for years, and they were very effective especially against post nasal drip. Then one day some of the spray went down my throat and I got thrush. After that I reduced my usage and finally just stopped using it.
During the last phase of my usage of these sprays I noticed my sense of smell declining especially for coffee. Over the next ten years I lost 80% of my sense of smell.MRIs and “nasalectomies” found nothing wrong with my sinuses. It is hard to enjoy cooking when your sense of smell is impaired.
I now use quercetin for my allergies. Quercetin is the basis for NasalCrom I believe.
Luke
Nasalcrom is pricy but I get it cheaper online. Sometimes I find the generic and it works just as well. I have been using it for many years daily and never had a problem with it.
Isabelle
Yes..yes…yes… I am a very big fan of NasalCrom…….I usually only have to spritz once to get a whole day of relief…..I always have to get my pharmacist to special order it because it isn’t stocked because big pharm can’t make money from it. ..(my personal humble opinion)
Don’t hesitate to ask for it….they don’t mind ordering it.
AND just because it isn’t advertised like crazy, doesn’t mean it doesn’t work!
Thank you for what you do….so necessary to bring balance and much needed information to us.
Isabelle
Derrick
I have used it since it first came to the U.S. as a prescription medication in 1983. My allergist recommended and prescribed it. I have used it every spring since then. Would not ever want to be without it.
Sharon
I have used sodium cromylgate nasal spray for 15 years, and it has been the only product that significantly reduces my tree pollen allergy symptoms. But now I cannot find it anywhere in Canada. It appears that it did not get a good share of the market so they have stopped producing it, and I am suffering a lot this year!!
How can I find this product? Help please!
Karlene
I cannot remember the year when I started using NasalCrom, but I went into the Rite Aide and picked up a box ( total satisfaction).
The strangest thing about NasalCrom is that it is good for every season.
I never finished a bottle because every year I would buy one bottle at the start of allergy season, spray my nostrils about 4 times a day for about 4 to 6 weeks, and that was enough the entire year. You know I picked up NasalCrom because it was the cheapest one, but as it turns out it was absolutely the better choice. I love NasalCrom. Unfortunately, it was not on shelf this past week. I hope that doesn’t mean it’s discontinued.
Allison
I’ve been using NasalCrom very successfully for a few years now, ever since my pharmacist recommended it. Clears up my spring and fall allergies with one spritz a day in the a.m. The trick is to start it before the season begins.
I also have a runny nose 365 days a year but that clears up when I forego or limit dairy. ?
Gail
Would NasalCrom be OK for someone who is allergic anti-inflammatory drugs ?
Jim
I have chronic sinus drainage in all seasons. Drs. have suggested that I have chronic sinusitis. I take loratadine, which I found to be the most effective OTC antihistamine, but it doesn’t stop all the drainage. I have tried corticosteroid sprays, and they produce spontaneous nose bleeds after a few days of use. I have tried antihistamine sprays, and they aren’t effective. Based on reports on PP, I tried cromolyn nose spray, and it turned out to be very helpful. The combination of loratadine and cromolyn give me the best control (but not total elimination) of nasal drainage I have ever had, whether OTC or Rx.
Carol
I recommended Nasalcrom to my mother, but it doesn’t seem to be available anywhere except from third-party sellers on Amazon and Walmart.com. Walgreen’s, CVS and Rite-aid all show it as out of stock online and in stores. Has it been discontinued?
Karen
I don’t have to use it more than once a day. Maybe the first 2-3 days, I’ll use it twice a day, then once daily works great. Many people would benefit from this great side effect-free medication.
O.G.
I keep suggesting Nasalcrom to people… and most of them haven’t tried it yet. I’ve used it for years and find it very effective.
Oh, well…
Emily
Just a heads-up in terms of side-effects of Cromolyn. I’m sure that my reaction was rare, but when I took it for asthma, I experienced severe dizziness, and my balance became so profoundly affected that I literally could not stand up or walk without falling. I checked with the pharmacist (my physician didn’t get back to me for a week), and he told me that this is a known, if uncommon side-effect. When I stopped taking the Cromolyn, my balance returned to normal. So if someone experiences this after starting to use Cromolyn, you should consider the medication before assuming that you have an ear or neurological issue.
As some other readers have commented, quercetin is an herbal remedy that suppresses histamine production by the mast cells, which I use with good success during allergy season. Starting to take it a a month before your symptoms usually appear helps it to be more effective.
Lea
Thank you so much for introducing me to NasalCrom. I had suffered severe seasonal allergies for years. Then a few years ago I tried NasalCrom. At first I had to use it three or four times a day, but it worked quickly and now during allergy season I need it only once in the morning and again at bedtime. In the winter I need only the bedtime dose every other day or less. It is wonderful, and I thank you again.
Cher
I have damage to my olfactory nerves from using Zicam about 15 years ago. I am not able to use typical nasal sprays, as I lose my sense of smell while using. I’m wondering if I will be able to use Nasal Crom or if it will also irritate my olfactory nerves (what is left of them)? Can anyone provide any insight?
Richard
I have has sinusitis since I was knee high and probably before that so any news about antihistamine alternatives is good news. I’ll let you know if it works!
Larry
Okay, I just read an article which explained why COVID-19 is so hard to treat once the lungs are involved: kinin storms!
Doesn’t this suggest a good preventative or treatment for COVID-19 is Cromolyn Sodium? Why isn’t this being used? Why aren’t we hearing more about it?
Judy
After I read an article in the People’s Pharmacy about NasalCrom several years ago, I started using it regularly. It completely stopped my allergic symptoms from pollen which I had had for over 50 years. It was miraculous. After my first use of it for a couple of weeks in the middle of allergy season I needed only two sprays a day.
About two years ago I started taking quercetin as an antioxidant. Then I read that it has the same effect on mast cells as NasalCrom so I stopped taking NasalCrom and my allergies didn’t come back. So I highly recommend both things, whichever is convenient. I do slightly prefer taking pills to putting a spray nozzle up my nose.
Donna
I suffered from hay fever since childhood and hated the drowsiness of antihistamines or intermittent surges of medication from combination pills with antihistamines and decongestants. For seven years when pregnant and nursing my three children, I took nothing. Then I tried Nasal Crom and was thrilled to feel relief without the negative side effects. It is not easy to find in pharmacies and have ordered it by mail the last few years. I estimate it only costs about $25 per season. My husband calls it my miracle drug.
Vera
I found that taking quercetin daily as a supplement works wonders to control my seasonal allergies. No need for allergy pills or antihistamines now.
Mike
I’ve been using NasalCrom for about 5 years and it has been a godsend! I suffer from seasonal allergies – mainly grass pollens and fungal spores which are prevalent in the summer months here in the southeast – and for years i suffered through months of clogged nasal passages and recurring sinus infections. For relief i used a number of different nasal steroid sprays – which were effective – but with pretty nasty side effects. i developed cataracts at age 40 and discovered i was developing glaucoma due to steroid sensitivity. One of the steroid sprays also caused a weakening of the nasal membranes resulting in severe nosebleeds. i learned about NasalCrom from The Peoples Pharmacy and gave it a shot…. It’s best to begin in the ‘offseason’ as it takes a few weeks to really work – and you won’t see a difference right away if your allergies are in full wing.. i use it the morning. at bedtime and before i head out and that does the trick – no more clogged nasal passages. There used to be a product called OptiCrom that was a mast-cell stabilizer for the eyes, but that is off the market – however i have found that prescription Pazeo drops (Oloptadine) work the same way – by stabilizing the mast cells around the eye. Now i don’t dread the summer months anymore!!!
Amy
Pittsburgh
I started using NasalCrom in the 80’s for severe hay fever as a teenager. It was a miracle drug for me. I used it for about 10 years, and then suddenly I no longer suffered from hay fever. I had run out of it and didn’t take it for a few days instead of buying more and realized I didn’t need it. I have not had any hay fever since. I did have allergy to cats, and if I was cleaning a dusty area I would have symptoms but both were manageable by just getting away from the source.
Unfortunately I just got a new Shih Tzu puppy, and within 24 hours it was obvious I am allergic to him. I have a black lab I have had for 4 years with no allergies. I have had several dogs in my life, and no allergies to any of them so this was a shock. I went out and tracked down a bottle of NasalCrom, and I am hoping it will work like before and let me keep this puppy. Otherwise I am gonna devastate my son cause it’s his puppy to raise.
I got Zyrtec to take also. Just really hoping this works. One dose of NasalCrom, and I felt a lot better for an hour then symptoms came back. I am hoping after multiple doses I will be able to keep this puppy and not have to break my son’s heart.
I also wanted to say I had told people NasalCrom cured my hay fever, and no one ever believed me. I see here that others said it did the same for their allergies here, and they were able to stop taking it. It’s an interesting phenomenon but there is no other explanation for why mine disappeared and I have had no trouble for 20 years. I had severe hay fever for many years and it just stopped. Fingers crossed it will do the same with this puppy or at least reduce symptoms enough that I can tolerate it.
Mike
California
Thank you for shedding some light on this product. Ive used it for years and it has truly been miraculous for me. I suffered for years with allergies and probably tried every medication out there. They all had serious side effects or lost potency quickly or both.
I’ve been puzzled as to why so little is known about it and why it is so hard to obtain. My guess is there’s not enough money to be made with this product since it works so well and even seems to permanently diminish allergies over time. Big pharma would love to see this medication disappear.
Fran
Nevada
I have used this product for 20 years and found it highly effective with no side effects. It was suggested to me by an allergist.
Ed
Baltimore
I Live in a major metro area and no one stocks it – even the stores listed on Nasalcrom’s website don’t have it. Then I was curious who makes it – the only name I can find is Prestige Brands – a conglomerate that owns everything from Spic and Span to Dramamine. So who knows where it is made – and the efficacy of the manufacture and use of this product.
If it is so good, why aren’t physicians and pharmacists recommending it? Is cromoglicic acid with sodium so alien in the medical community that folks don’t know about it? One pharmacist drew blank stares when I told her it is Cromolyn Sodium which addesses mast cells production of histamine – is this stuff really legit?
Kathy H.
TX
It is a great product. I have been using it since my Dr prescribed it over 30 years ago when a prescription was required. I can no longer find it in retail stores and get it online.
Lacy
Seattle
Where can I buy Nasal Crom?
Denise
Okc
NasalCrom is wonderful and really works! Is that why it has been discontinued? Because it is non-habit forming and the pharmaceuticals want you hooked on the others???
Donna
WashingtonDC
NasalCrom actually works BETTER for me than the allergy pills that cause side effects. I’ve been telling everyone about it for several years. It gets a lot of word-of-mouth recommendations, and I think that’s why we don’t see a huge advertising budget for it. There is nothing to lose as it doesn’t have any dangerous side effects. Just be sure to give it a full week before making a final decision, as it takes several days to “kick in” but then it is WONDERFUL. Rather than addressing symptoms you already have, it prevents you from having the symptoms in the first place. So it feels like I am now back to being a person who just doesn’t have allergies!
Jennifer
Kentucky
I agree; NasalCrom is much more effective and fast-acting than many of the oral medications I’ve tried. I live in Kentucky and have severe grass and tree allergies that turn me into a sneezy, weepy, red-eyed disaster each spring; however, NasalCrom has done wonders for me. I’ve used it for more than 10 years and have had no issues with it at all. I only use it when pollen levels are forecast to be high or when I’m going to be exposed to specific allergens- I can usually spray a few minutes before mowing the lawn and have absolutely no issues; my husband, who is allergic to cats only uses NasalCrom when he is going to be in close proximity of them, and after he sprays each nostril, he is symptom-free (as long as he doesn’t rub his eyes after petting a cat) for a good 2-3 hours. It has been a game changer for us!
Karamah
Apopka, Fl
Your article is so refreshing because NasalCrom is one of the medical profession’s best kept secret, here’s my story
In 2000 I had my worst ever persistent headache, I was sure I head a tumor, so after a co-worker died from a brain tumor I was convinced that I had one also. I went to see Rob, my then PCP and said, “Rob, I have a brain tumor!!!” I described my headache, which more severe in the back of my head, and mild in the sinus areas. Rob examined my nose, my ears listened to my chest and gave me a prescription for NasalCrom, it wasn’t sold over-the-counter back then. What I like about this doctor had always been his right on conservative treatment of disease processes. But my immediate response was, “ Rob, the pain is in the back of my head!” He responded, “ your ears are very congested”. I was already familiar with Cromolyn Sodium because a pediatric allergist, co-worker, had prescribed the inhaler when I was diagnosed with asthma in the mid 1970s. With a big question mark on my face I took the prescription, filled it, and use it and “voila”, brain tumor gone, no more headache, no more severe itchy eyes( I had deep black circles and rough looking eyelids from constant rubbing and scratching) no more rough black skin. I have used religiously since and recommend to everyone I meet who is experiencing the discomforts of allergy symptoms. I just tell them I would be just as uncomfortable without NasalCrom, show them the bottle, it is always in my purse, discuss the price and tell them it’s worth it. Those that use it love it just as much as I do. Thank you for the opportunity to share this.
With gratitude,
Karamah
Barb
Illinois
Should have been using this product. Instead, my doctor told me to use Flonase or Nasacort. Bad advice because I developed cataracts soon after and now am developing glaucoma. This side effect is in fine print. Optometrist said steroid nasal sprays should only be used for a very short time.
DEANNA
TEXAS
Nasalcrom has been a lifesaver for me. Thank you for the article. I trust your opinions. I decided to give it a try and my allergies are under control for the first time in YEARS!!!
Ray
atlanta
excellent in controlling my allergy and cold symptons
Jody
WA
I used NasalCrom for several years at the first sign of my “spring allergies” kicking up. Eventually I got to the point where I was no longer allergic! I believe that preventing allergic reactions helped my body stop producing the IgE that made me prone to those reactions. It’s been over 15 years now and I have not starting reacting again.
However, I have developed an allergy to flea bites. I may go back on it and see what happens . . .
Kathy
Kentucky
I have used Nasalcrom for over 15 years, and most of my allergy symptoms were gone, and I have suffered my whole life with a constant stuffy nose. When I couldn’t find it this past spring and summer anywhere I felt desperate and tried some of those other nasal sprays which didn’t work. On a fluke I searched online, and, “Praise God,” found it there. I now have it auto-delivered about every 5-6 weeks. The first few months I had to use at least 4 times a day but after awhile only morning and night. I really don’t know what I’ll do if I can’t ever find it aagain!
Jan T
California
Please let me know if anyone knows of a source for Intal spincap Inhalers (which are cromolyn based). It is inhaled through a Spinhaler.
Alternatively, if anyone knows of any kind of cromolyn sodium that would be useful for people with asthma, please forward information to me. Intal was a great product and should NEVER have been removed from the market! I need to get off steroid inhalers. Please help!
Grace
Michigan
I have used most all the nasal sprays over the years, and because of these I have no sense of smell. I would like to try Nasalcrom but cannot find it anywhere. Tried all the pharmacies and health food stores. Can someone please help me find it??
Paul
Here in eastern Washington I have bought Nasalcrom at Rite Aid.
Paul, WA
Gina
Texas
Grace, the official NasalCrom website has a “where to buy” page. That’s how I found it in a local store. Make sure you search for the .44oz AND .88oz — these are often found at different stores.
Randall
Indiana
Grace, I love Nasalcrom; it works far better for me that any of the alternatives. Sadly, I never see it in stores, so I just buy it from Amazon. The manufacturer doesn’t seem to advertise this product, but I’m glad it’s still made. Hope they keep making it. Good luck!
Dana
Missouri
I bought mine from Amazon.
Kathy
Amazing product!
Tina
Virginia
I just bought some at Rite-Aid.
Bob
chicago
My allergies had always been horrible until I started using Nasalcrom in the early 1980s. Since then, I have had little-to-no problems and NO side effects. The only problem is that recently Walgreens has stopped carrying it and I’ve had to order it online.
Mo
Arizona
I just started Nasalcrom two weeks ago because my nebulizer Cromolyn Sodium was discontinued. I’m unable to take steroids and my doctor said I could order it from Canada and the price is prohibitive so I decided to use Nasalcrom since my doctor is out of ideas. I like it so far and I’ve had no asthma attacks but I still get a bit of an allergy cough. I really think it’s a wonderful product.
Angie
Springfield, MO
After reading the comments regarding Nasalcrom, I decided to give it a try. Although congestion is not an issue for me, I suffer from inflammation, itching, watery eyes, and a bitter, sometimes burning sensation on my tongue. Mast cell inhabition was an appealing approach to my battle to control inflammation and allergic responses.
However, after doing additional research, I learned one of its ingredients, benzalkonium chloride, is extremely toxic; therefore have discontinued its use. As a result, I question the support of the product by People’s Pharmacy. Can anyone shed additional light on this information?
Paul
Eugene, OR
Angie:
Many chemicals can be toxic at high levels and perfectly safe (and even necessary for good health ) at low levels. Iodine is a good example.
Many anti-bacterial soaps and lotions have contained benzalkonium chloride at levels of up to 5%. At those levels, I can understand why it would be toxic. From my research, however, I have found the following ingredients in Nasalcrom: Each milliliter of Nasalcrom Nasal Solution contains 40 mg cromolyn sodium in purified water with 0.01% benzalkonium chloride to preserve and 0.01% EDTA…
An Abstract published at PubLMed.gov (National Institutes of Health) provides the following information (I encourage you to read this carefully):
Safety review of benzalkonium chloride used as a preservative in intranasal solutions: an overview of conflicting data and opinions.
Marple B1, Roland P, Benninger M.
Abstract
BACKGROUND:
For most multiuse aqueous nasal, ophthalmic, and otic products, benzalkonium chloride (BKC) is the preservative of choice. The American College of Toxicology has concluded that BKC can be safely used as an antimicrobial agent at concentrations up to 0.1%. [NOTE THAT NASALCROM has a concentration of .01%, which is 100 times less.] BKC has been in clinical use since 1935 and is contained in a wide variety of prescription and over-the-counter products. However, over the past several years there have been conflicting reports of damage to human nasal epithelia and/or exacerbation of rhinitis medicamentosa associated with intranasal products containing BKC.
OBJECTIVE:
We sought to review the published literature and determine whether there is sufficient, clinically significant data that would confirm that intranasal products containing BKC are likely to damage human nasal epithelia or exacerbate rhinitis medicamentosa.
METHODS:
A literature search was conducted for in vivo and in vitro studies that evaluated the effects of BKC on human nasal epithelia.
RESULTS:
A total of 18 studies (14 in vivo, 4 in vitro) were identified that evaluated short- and long-term exposure of concentrations of BKC in concentrations ranging from 0.00045% to 0.1%. Eight studies, including a 6-month and 1-year long-term treatment study, demonstrated no toxic effects associated with BKC, indicating that BKC was neither harmful to nasal tissue nor prone to exacerbate rhinitis medicamentosa. Furthermore, of the 10 studies that concluded that BKC resulted in degenerative changes in human nasal epithelia (eg, ciliary beat frequency, ciliary morphology, mucociliary clearance, epithelial thinning and/or destruction) or that BKC exacerbates rhinitis medicamentosa, only 2 (it was 2 according to the Results section) of these studies were supported by statistically significant differences between BKC and placebo or active control groups were compared. It is important to note that in both of these studies, the protocol incorporated the use or oxymetazoline in some or all of the subjects. Oxymetazoline is associated with rhinitis medicamentosa.
CONCLUSION:
Intranasal products containing the preservative BKC appear to be safe and well tolerated for both long- and short-term clinical use.
Paul’s comments continued: Of course, if the use of Nasalcrom causes excessive stinging and/or irritation for you, stop using it. I have used Nasalcrom for about 25 years and it has been the safest and most effective drug I have ever used. I had the worst sinus allergies imaginable and after using Nasalcrom for several years, I started using it less, and less, and less and finally, I went several years without using it at all. It literally cured my allergies. When I finally started mildly suffering from allergies again in the early spring, I resumed my use (only about twice a day for about six to eight weeks) and I was once again allergy free. I am about to start using it again twice a day as spring is near and I am beginning to see flower buds appearing on some trees.
Ro
Illinois
I really like using Nasalcrom and have used it since it came out, but every pharmacy/pharmacy department I’ve been to no longer carries it, so I ended up ordering it online.
Dick
Florida
is it advisable to add Chromolyn to a fluticasone nasalspray regimen
Hank
left coast
Back when people smoked tobacco indoors, I used cromolyn sodium all the time (lifetime tobacco allergy). Very effective stuff.
Jeianette
West Seneca, NY 14224
Where can I purchase NasalCrom?
Thank you
Jeanette Z
Richard T
South Africa
I live in South Africa and have a problem with sneezes that go on and on. Closest product I can find is called Stop-Allergy eye drops containing sodium cromoglycate. I decided to use it sprayed up my nose in a fine mist and used when the first sneeze starts it stops me sneezing further. Thanks for a useful bit of advice.
Healthnut
I buy Veriditas essential oils and have found that using peppermint in boiling water helps clear congestion instantly! I also put it on my clothes to where I can smell it when I go out and it also helps.
RWW
WI
I have been using NasalCrom since the mid 1980s. Before that I had severe allergies that shots could not help. I had allergies year round with many sensitivities.
After starting NasalCrom…no more shots or antihistamines. I have been virtually allergy-free unless I stop using Nasalcrom. Even then I am much better.
Mary
OH
Really? I am suffering and suffering with allergies! Do you use this with another spray or just this spray? I am using Flonase along with Allegra. I need more help.
Anon
U.S.
I had completely forgotten about NasalCrom. I took it in the early ’80s and it worked like a champ! Wow. This was a blast from the past and I’m glad I read it. I incorrectly thought it was an antihistamine. I am passing this article along to a friend whose mother has tried everything.
jan
California
I have used cromolyn inhalers (Intal) for years through a spinhaler..and loved it! No steroids! Then, it was no longer offered in the proper dose, with the advent of a myriad of steroid inhalers hitting the market.
NasalCrom works as promised, too, and it is definitely worth trying FIRST before adding steroids!
Thanks so much for posting this advisory!!
Jenifer A.
Southern California
I read your piece on NasalCrom with keen interest. I am allergic to pet dander and ragweed, among other things. I take cetirizine daily to allow me to be near my son’s dogs (whom I love) and to function outdoors. I read that NasalCrom can have long-term negative effects on nasal mucosa (“Benzalkonium chloride in nasal decongestive sprays has a long-lasting adverse effect on the nasal mucosa of healthy volunteers.”
Hallén H, et al. Clin Exp Allergy. 1995.) I would appreciate your comments on this study.
Marie
Florida
I used cromolyn for a year in the early 90’s and complained many times to my allergist who had prescribed it that it burned my nose. He insisted that I keep using it, even saying “his family used it and had no problem”. I stopped it on my own but by the time I did, I had lost most of my sense of smell which never recovered. No cromolyn for me!!!
Sandy
Dallas, TX
I’ve been using Nasalcrom for years. It’s one of the three or four sprays that I do use. I also use XClear and a homeopathic spray. I recently found Rebound which helps with congestion, but I try not to let it get that far.
Gloria
Ohio
Has anyone tried this and how did it work for you?
Dave
Reidsville, NC 27320
Nasal Chrom WORKS ! The down side of it is actually an up side. Using it conveniently 4 times a day provides rinsing, nasal moisture AND mast cell control. I have used it when first signs of nasal allergy comes along for several years. It also avoids almost inevitable nasal tissue rebound from a product like AFRIN.
Another really helpful, extended use, maintainance, nasal spray is, in my experience, X Clear. It too rinses / moisturizes and, in my experience, promotes sinus and ear drainage. It can be used along with other nasal treatments. The X refers to XYLITOL which, in chewing gum, has been reported to help children with clearance of mucous in the ears.
With NasalChrom and X Clear I have dropped all but rare use of regular allergy capsules.
Dave
Reidsville, NC 27320
Nasal Chrom WORKS ! The down side of it is actually an up side. Using it conveniently 4 times a day provides rinsing, nasal moisture AND mast cell control. I have used it when first signs of nasal allergy comes along for several years. It also avoids almost inevitable nasal tissue rebound from a product like AFRIN.
Another really helpful, extended use, maintainance, nasal spray, is, in my experience, X Clear. It too rinses / moisturizes and apparently promotes sinus and ear drainage. It can be used along with other nasal treatments. The X refers to XYLITOL which, in chewing gum, has been reported to help children with clearance of mucous in the ears.
With NasalChrom and X cLear I have dropped all but occasional use of regular allergy capsules.
Charles
I lived in NE Greece at the time.
I used Nasalcrom for several years around 2000. It worked as advertised, but during that period I almost totally lost my sense of smell. That’s the reason I stopped using it. I can still smell a skunk, but little else. A few years ago I scanned the web for any mention of a class action lawsuit, but I didn’t find one. I did find one for something that looked like a similar product.
Vi
PA
I have used Nasalcrom (first prescribed by an allergist) and have found it superior to all the others. But sometimes it is not in stock and has to be ordered.
I also had severe sinus congestion, in my upper sinuses. This clear, viscous material would suddenly drain for an hour every 24 or 36 hours. Terrible! I cured it in 1 week with anti-fungal medication!
Michael
Tucson
Back in the ’90’s I suffered from allergies, especially in the fall. I would use Duration nasal spray and became hooked on it due to the rebound congestion. I ended up having to use it year round. It became a nightmare.
I went to my PCP, here in Arizona, and told him I had been on Duration for several years and could not get away from using it. He RX’d Cromolyn Sodium (NasalCrom) to me to break the cycle. I quit using Duration and only used NasalCrom as directed. Within two weeks, I was off Duration and no longer needed NasalCrom. It is a wonderful medicine to use.
Barbara
spokane
Toothpick weed is amivisnaga, and like many in the carrot family, it is hard to tell the difference between the toxic species and the beneficial and edible plants. That said, there is some literature on the use of this herb to treat kidney stones as well as asthma. Wonder what big Pharma got the patent on that??
Just googled it…it is not the same as the ornamental Bishop’s weed, ska snow on the mountiain…which in some state with (IMO)picky conservationists, is listed as a noxious weed because it spreads fast.
Barbara
Spokane WA
A perennial called Bishops Weed is a common garden plant around here…would planting it around the porches help I wonder??
Ellen
Texas
I’ve used (and recommended) Nasalcrom since 1980(!) when it was a prescription medication. My wonderful doctor in Houston found it looking for something his daughter could use that was safe and effective. It is so safe, the accompanying literature states, pregnant women can use it. It does not interact with other medications.
I still use it. The prescription was stronger, but much more expensive. Now it is very reasonable, but you may have to use more often. I recommend it often. Since it’s “over the counter” now and inexpensive compared to the newer allergy sprays, it’s definitely worth a try.
Beth
So. California
I have had allergies for years, and Allegra has been used. But this season, I was hit really, hard. I just turned 80, and have Glauoma, so I have to be careful. My doc prescribed Prednisone because I was so inflammed and it was affecting my scarred lungs. I have tried over the counter stuff, and nothing is helping. I guess I can get this at the drug store. I will certainly give it a try. Thanks.
Pam
Pennsylvania
This article left me curious about the role of mast cells in atopic eczema, and whether cromolyn would be helpful if applied topically to eczema rashes. Any thoughts?
Kangavkar
Houston, TX
Dear Sir/madam,
I was using Cromolyn nasal drops. At this time, it is NOT available in the US. Has it been re-introduced in the market? Please let me know. Thanks.
Kathy
North Carolina
I’ve not tried NasalCrom, but I’ve gotten good results with Xlear Nasal Spray (with xylitol). Do you have any comments on Xlear? Thank you.
Mary
Greensboro, NC
Can you use NasalCrom in combination with other products?
Alice
Dallas, TX
My ENT doctor told me to use Nasalcrom because I have glacoma and had to avoid steroid nasal sprays. After I had used two bottles of Nasalcrom I lost my sense of smell. That was 3-4 years ago and I still can’t smell.
Lyn
I’ve been using NasalCrom for years and love it. I have reactions to steroid sprays, this simply encapsulates the histamines so they don’t make one’s eyes and nose run, and it has virtually no side effects, nor does it have adverse consequences with other medications.
I use NasalCrom twice a day during the pollen season, and it works extremely well. My Dr. suggested this over-the-counter spray, and it can be purchased at Bartell’s. I haven’t found it anywhere else in our region. I’d give this med a five star.
Aster
I started using NasalCrom over a year ago. I use it 2 to 3 times a day. My allergies are very bad. I have seasonal allergies and am allergic to tree and weed pollen as well as indoor allergies to dust mites and my cats. I sneeze all year round. I have been on allergy shots for years and took numerous medications, including Zyrtec.
I have been wanting to get off of Zyrtec but didn’t know how. Other antihistamines were not as effective. Since I have been using NasalCrom, I have had zero symptoms from allergies. I am now to the point where I feel confident enough to try getting off of Zyrtec. This is by far the best nasal spray for me. Very happy to have found it.
Bob
WV
NasalCrom is a life saver. I use it only when I get a nasal “itch” and it work immediate wonders. No side effects. No dependencies.
O.G.
SC
EXCELLENT stuff, NasalCrom! I’ve been using it for years, and recommending it to anybody who will listen. So much better than antihistamines and OTC nasal sprays.
Thank you for featuring it: it deserves to be better known.
(PS: I live in the pollen-covered South. ?)
Earl
Durham, NC
I have been taking Quercetin for since 2002 and have had zero problems with allergies since. Before 2002 I was miserable, headaches, itchy eyes, running nose, tears, tears, tears.
With Quercetin it has to be built up in the system. I take it daily; I started two months before allergy season initially every day and since. I recommend it.
Carol B
North Carolina (NC)
Wondering how effective Nasalcrom is on allergic asthma? Is it strong enough to maybe prevent an attack and does it interact with emmergency inhalers if the problem is not solved?
Sometimes I think my asthma begins with allergies mold or trees, and often leads to ER visit in spite of my rescue inhaler.
Thanks and I love your column!
Carol
Dallas, TX, USA
Can you use NasalCrom if you have glaucoma?
Liz
Is it safe for kids? My 8 yo granddaughter suffers miserably from allergies
Ann
MD
I have been on corticosteroid nasal sprays for 40 years and sometimes they stop working. I use Nasacrom and it gets me back on track. Ann H.
CR
LA
Just wondering if it would help for pet allergies and household dust.
Marilynn
NE Illinois
Effective, but uncomfortable to use.
I used it as a prescription in the 80’s and 90’s. One negative is that it is very watery and runny making me feel like I had snuffed water up my nostrils. Like I was drowning. That is why I prefer Fluticasone. It is thicker, less watery, and works just as well.
Judy W.
Maryland
I tried NasalCrom when it first came out but I think I didn’t use it long or often enough, and it didn’t work. Thanks for writing about it. My allergy meds never work completely during the heavy pollen times, and I can’t take shots because after years of effective shots I had an anaphylactic reaction. I didn’t realize it’s over-the-counter now, and I’m going to try it.
Ed
Florida
In the mid 2000’s I was experiencing a recurring cycle of sinus infections. For years I was cycling on and off of antibiotics, Cipro,Levaquin, Avalox. I remember multiple cycles of 30 days on Levaquin. To keep the symptoms at bay and to be able to work, I used OTC cold remedies but nothing was working. I have since learned that so many antibiotics actually perpetuate the problem.
I went through allergy tests, immune factor tests, and other treatments with no results. My immunologist specialist gave up, and as a whim, on my way out the door he suggested nasalcrom. It saved my life and allowed me to get back in balance and I no longer suffer from nasal infections. I now use it very infrequently during pollen season.
KD
Connecticut
Yes!!!!!!!! Finally: more discussion about this remedy. And you do have to use about 4x/day. GO GET IT!!
Only ONE of my regular respiratory doctors (not my ENT nor pulmonologist nor osteologist) – my recent allergist – made me aware of cromolyn sodium! She called it “old fashioned.” Well, if it ain’t broke…
I first (and still do) used it nebulized, then discovered nasal spray brand NasalCrom. It is soooooo good. I did my own research after my 3rd – yes, 3rd polyp removal surgery (July 2016) and confirmed my experience using the spray. IT WORKS, and my polyps are smaller: I no longer trust my ENT doctor; still have to have that “chat” with him. Last week I had my drug store order more just for me to always have it on hand.
THANK YOU!?!!
Noah
Right Here
I have been using Nasal Crom since it was a prescription med and it has proven not merely effective, but so effective I will forget to use it every now and then. The one thing about all these other nose sprays is, when you need to use them they let you know via sneezing, drippy nose, etc, but with Nasal Crom just becaause you forgot to spray one or two times the effects last long enough for you to remember without having to suffer the indignities of allergy season.
I begin in mid-February/early march, depending how long Winter hangs around, and then finish up in mid- June or so.
As far as I am concerned this is the greatest stuff, ever, and when I stop using it, presuming my timing is right-on, my nose doesn’t run again unless I get a cold before the next Spring.
I used to sort of dread Spring with its several months of pollen, now I look forward to it again.